Saffron: The golden spice with excellent therapeutic properties for digestive ailments
Saffron is a natural compound that has been used for centuries in many parts of the world as a coloring agent and food additive. It has been shown to be able to mitigate various disorders through its anti-inflammatory and antioxidant properties.
Several studies have shown the effectiveness of saffron in the treatment of various chronic diseases such as inflammatory bowel disease, Alzheimer's disease, rheumatoid arthritis as well as common malignancies of the colon, stomach, lungs, chest and skin. Modern medicines often have unwanted side effects, leading to the current trend of people using naturally derived products with alternative therapeutic properties.
In this article, the blog Saffron Palace Vietnam will clarify more about the " golden spice" of saffron in the treatment of digestive diseases.
The effect of crocin contained in saffron
Crocin is the main ingredient in saffron extract that has effects such as anticonvulsant, antidepressant, anti-inflammatory, anti-tumor, enhancing learning ability and improving memory.
In addition, the role of this substance in saffron is also in the treatment of various disorders such as digestive diseases and psychological disorders.
In traditional Persian medicine, saffron is used to combat depression, with four randomized controlled human clinical trials currently underway to support it. However, saffron is not recommended for pregnant women because it can interfere with embryo development. Scientists have shown that saffron has few side effects compared to other ingredients. Their chemical components are said to have better compatibility with the human body.
Saffron affects the microbiome, molecular pathways and inflammation in gastric, colon, liver cancer and related inflammations.
The biological activities of saffron help in the treatment of digestive diseases
Saffron has four major bioactive components including crocin (C44H64O24), crocetin (C20H24O4), picrocrocin (C16H26O7) and safranal (C10H14O). They can be readily absorbed through the intestinal cells, and end up in the chylomicrons unaltered before being excreted into the bloodstream.
Several studies have shown the effectiveness of saffron components in various inflammatory digestive disorders, as well as the prevention and treatment of gastrointestinal cancers.
Numerous evidences have demonstrated the beneficial effects of the carotenoids crocin and crocetin on inflammatory disorders including gastritis and peptic ulcer disease, irritable bowel syndrome, inflammatory bowel disease, and hepatitis.
Saffron has the effect of treating gastritis and gastrointestinal ulcers
Many studies have concluded that crocin protects rat gastric mucosa against ethanol-induced injury by exhibiting anti-inflammatory, antioxidant, anti-apoptotic and mucin-secreting mechanisms, possibly mediated by increased release PGE2.
With its antioxidant properties, saffron has the potential to act as a preventer of gastric mucosal damage through the enrichment of glutathione content and the reduction of lipid peroxidation. These findings need to be further investigated through clinical trials to compare saffron with other therapies in the treatment of peptic ulcers.
Saffron has a good effect on the intestinal system
Gastrointestinal diseases affect approximately 60–70 million US citizens annually. Irritable bowel syndrome (IBS) is characterized by abdominal discomfort and changes in bowel habits, affecting 30 to 45 million US adults each year.
After some time, scientists discovered that Curcumin, contained in Indian saffron, has antioxidant and anti-inflammatory properties and has been shown to have beneficial effects in IBS patients.
Beneficial effects of saffron on hepatitis
Saffron has shown hepatoprotective effects mainly through its antioxidant properties. Effect of ethanol saffron extract (dry stigma of Crocus sativus L.) on liver tissue damage in streptozotocin-induced diabetic rats. Saffron improves antioxidant enzymes and inhibits lipid peroxidation and nitric oxide formation in aged male rat liver.
The ethanolic saffron extract had no toxic effects and no significant changes in liver and kidney function, indicating the obvious antioxidant capacity of crocetin and crocin in the liver. The anti-inflammatory components of saffron may be beneficial for various types of liver diseases such as drug-induced liver damage, viral hepatitis, and steatohepatitis.
Cancer prevention and treatment effects
Cancer prevention with natural products represents a promising strategy against cancer development and progression. Natural products with antioxidant and anti-inflammatory properties have been evaluated for their ability to suppress tumor growth and maintain tissue homeostasis.
Studies using animal models and human cancer cell lines have demonstrated the anti-cancer activities of saffron.
The above studies show that the prophylactic and therapeutic properties of saffron are mainly accomplished through its antioxidant and anti-inflammatory effects, inhibition of cell proliferation, induction of apoptosis and gene-protective properties.
The activity of these compounds on gut microbiota dynamics would be significantly improved. Saffron can help treat and improve intestinal, digestive or liver diseases. The active ingredients present in Saffron are an excellent anti-inflammatory agent. It is also an effective remedy for diseases of the gastrointestinal tract.
However, everyone should find a reputable Saffron shopping channel to avoid losing money. Only genuine, genuine saffron has great effects for consumers' health. To avoid buying fake Saffron Palace products, poor quality on the market, customers can transact with Saffron Palace at official channels:
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